"Borderline" (1984) Directed by Mary Lambert.
While gathering my archive of links to music videos that use Downtown as a location, I saw I missed Madonna's "Borderline" using the Arts District as a barrio back in 1984.
It reintroduces our informal survey quite nicely.
Locals will instantly spot the 4th Street Bridge at Santa Fe before the story switches back and forth from the loft of a photographer to a pool hall on 6th. (As always, extra points for anything shot in the Arts District).
The break dancers do seem to be lifted out of New York and not neighboring Boyle Heights. Still, it is interesting to see the Arts District used at the dawn of music video history, before it was called the Arts District.
Too much analysis of the song can be found at Wikipedia.